1. Naranjo ID, Lo Gullo R, Morris EA, et al. High-Spatial-Resolution Multishot Multiplexed Sensitivity-encoding Diffusion-weighted Imaging for Improved Quality of Breast Images and Differentiation of Breast Lesions: A Feasibility Study. Radiology: Imaging Cancer 2020 2:3.
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MUSE improves differentiation of breast lesions and image quality

A recently published study found that multiplexed sensitivity-encoding (MUSE) improved image quality and provided better lesion visibility compared to single-shot DWI. The study, High-Spatial-Resolution Multishot Multiplexed Sensitivity-encoding Diffusion-weighted Imaging for Improved Quality of Breast Images and Differentiation of Breast Lesions: A Feasibility Study, also found that MUSE ADC values demonstrated a significant difference between malignant and benign lesions, providing both qualitative and quantitative benefits1.
Designed to minimize artifacts by correcting for motion-induced phase variations in echo-planar imaging, the authors reported MUSE provided better signal-to-noise ratio (SNR) and achieved improved fat suppression and artifact correction compared to the single-shot DWI technique. The authors also found that the higher SNR and contrast-to-noise ratio (CNR) with minimum artifacts in the MUSE images enabled them to reduce the number of averages to decrease scan time and maintain image quality.
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